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Diseases associated with CTSS include Dacryoadenitis and Cerebellopontine Angle Tumor. Among its related pathways are Bacterial infections in CF airways and Degradation of the extracellular matrix. [Cathepsin S (CTSS) is highly expressed in temozolomide-resistant glioblastoma T98G cells and associated with poor prognosis]. Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma. Cathepsin S is a protein that in humans is encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this gene. Cathepsin S is a member of the peptidase C1 family and is a lysosomal cysteine protease that may participate in the degradation of antigenic proteins to peptides for presentation to the MHC class II. Cathepsin S can function as an elastase over a broad pH range in alveolar macrophages.
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View mouse Ctss Chr3:95526786-95556403 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression Gene. CTSS. Species Human Location. Chr.1: 150765835-150766345 on GRCh38; Amp. Len. 511 Transcripts. 2 RefSeqs (NM) Availability. Made to Order.
The following CTSS gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CTSS cDNA ORF which is encoded by the open reading frame (ORF) sequence.
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Cytochrome b5 type B. CYP11B2. Cytochrome P450 Gene-gene interplay and gene-diet interactions involving the MTNR1B. 421 armadillo repeat gene deleted in.
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Biological context of CTSS. The frequency of the CTSS-25A allele was 0.457 in Caucasians and 0.431 in Canadian Inuit. Because of the importance of the CTSS gene product in vascular matrix remodeling, this polymorphism may be useful in the study of associations with atherosclerosis and related phenotypes. 2020-07-01 · The turbot CTSS genes were captured from turbot genome and transcriptome database by BLAST program using sequences of CTSS genes from other vertebrate species as queries, with a cutoff E-value of 1e −10 [38,39].
4.3 Summary of the CAGEexp experiment slots and assays.
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cathepsin S. Synonyms. Cat S Feature Type.
Gene therapy helps treat a disease at its source. It's used to fix, turn off or add genes to your genetic code. 2011-04-01 · The following TaqMan Gene Expression Assays (Applied Biosystems, Foster City, CA, USA) were used for cDNA transcript quantification: Hs00374176_m1 for CD40 (exon boundary 1–2, amplicon length 101), Hs00175403_m1 for CTSS (exon boundary 3–4, amplicon length 82), Hs00947433_m1 for CTSB (exon boundary 2–3, amplicon length 73), and Human PPIA (cyclophilin A) Endogenous Control (4326316E) as
UCSC Genes CTSS (uc001evn.3) at chr1:150702672-150738433 - Homo sapiens cathepsin S (CTSS), transcript variant 1, mRNA. CTSS (uc010pcj.2) at chr1:150702672-150738433 - Homo sapiens cathepsin S (CTSS), transcript variant 2, mRNA.
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